One nice thing about throwing stuff on the internet is sometimes someone looks at it.
Last week I got an email from the grandson of the mystery couple in this picture:
The man in front is Fred J. Ackermann, RPh, and the woman on the left is Helen Campbell Ackermann. Fred was the pharmacist and partner of my grandfather Walter Coulter in the restaurant and pharmacy at the corner of Sloane and Detroit in Lakewood, Ohio. He also confirmed my assumption that the other couple are my grandparents.